
Underneath the hood
When we started profiling the performance of adblockers, we found that commonly available block lists are of great quality and can block a lot of ads. But,, many extensions spend a lot of time checking whether URLs or page elements occur in their block lists. Opera checks the block list using native code and fast algorithms, making the slowdown from checking negligible. Furthermore, Opera blocks ads as early as possible: right in the engine, when a network request for a URL is first being made.
Opera currently uses block lists from EasyList, both the regular EasyList to stop advertising and the EasyPrivacy list to stop trackers.
http://www.opera.com/blogs/desktop/2016/03/native-ad-blocking-feature-opera-for-computers/
http://get.opera.com/pub/opera-developer/37.0.2163.0/